Part 1: Autoimmune Hemolytic Anemia
Thomas G. DeLoughery, MD
Professor of Medicine, Pathology, and Pediatrics, Division of Hematology/Medical Oncology,
Departments of Medicine and Pediatrics, and Division of Laboratory Medicine, Department of
Pathology, Oregon Health Sciences University, Portland, OR
A 37-year-old man who was diagnosed with warm AIHA several months ago presents for a follow-up visit. He responded to prednisone therapy but cannot be weaned off steroid therapy as his hemolysis flares whenever his dose is decreased under 20 mg per day. He has also developed diabetes and had a flare of his chronic hepatitis B when he first started high-dose steroids. He is otherwise healthy. What is the next most reasonable option for therapy?