Part 1: Transfusion Medicine

Thomas G. DeLoughery, MD, FACP

Professor of Medicine, Pathology, and Pediatrics, Division of Hematology/Medical Oncology, Knight Cancer Center, Departments of Medicine and Pediatrics, and Division of Laboratory Medicine, Department of Pathology, Oregon Health Sciences University, Portland, OR.

Question 4

In which of the following patients would it be most appropriate to consider granulocyte transfusions?

  •   Patient with chronic lymphocytic leukemia with mucormycosis after receiving
    alemtuzumab with a white blood cell count of 1 × 109/L (100% neutrophils)
  •   3-year-old child 35 days out from start of chemotherapy for acute lymphocytic
    leukemia (ALL) with a neutrophil count of 0 and invasive aspergillosis
  •   18-month old child with fevers and positive blood cultures for Staphylococcus
    aureus 3 days after starting chemotherapy for ALL with a neutrophil count of 0
  •   45-year-old man 35 days out from start of chemotherapy for acute myeloid
    leukemia with a neutrophil count of 0 and invasive aspergillosis

Updated 02/15/2012 • jdw | Copyright ©2013 Turner White Communications