Part 1: Transfusion Medicine
Thomas G. DeLoughery, MD, FACP
Professor of Medicine, Pathology, and Pediatrics, Division of Hematology/Medical Oncology, Knight Cancer Center, Departments of Medicine and Pediatrics, and Division of Laboratory Medicine, Department of Pathology, Oregon Health Sciences University, Portland, OR.
A patient who was admitted to the intensive care unit for a major gastrointestinal bleed receives a red cell transfusion. One hour after the transfusion, he complains of severe dyspnea. Over the next 30 minutes he develops respiratory failure and fevers with a chest x-ray showing infiltrates. He is intubated, but over the next 24 hours he improves and is extubated in 48 hours. What reaction is this scenario consistent with?