Part 2: Immune Thrombocytopenia

Thomas G. DeLoughery, MD, FACP

Professor of Medicine, Pathology, and Pediatrics, Division of Hematology/Medical Oncology, Knight Cancer Center, Departments of Medicine and Pediatrics, and Division of Laboratory Medicine, Department of Pathology, Oregon Health Sciences University, Portland, OR

Question 2

A 34-year-old man has been treated for ITP with 2 courses of prednisone over the past year. Prednisone therapy raised his platelet count to 75 x 103/µL, but with both steroid tapers it decreased to 3 x 103/µL. With low platelets, he has suffered increased bruising. Which of the following options is associated with the highest rate of long-term remission?

  •  IVIG 1 g/kg every 28 days
  •  Splenectomy
  •  Romiplostim
  •  Rituximab 375 mg/m2 weekly for 4 weeks
  •  Eltrombopag

Updated 6/01/2011 • jdw | Copyright ©2013 Turner White Communications