Part 1: Disseminated Intravascular Coagulation
Thomas G. DeLoughery, MD, FACP
Dr. DeLoughery is a professor of medicine, Departments of Pathology and Pediatrics, Oregon Health Sciences University, Portland, OR.
Given that the underlying mechanism of disseminated intravascular coagulation (DIC) is inappropriate activation of thrombin, treatment with an anticoagulant is appealing. However, antithrombin therapy should be strongly considered in only one of the following situations: