Immune Thrombocytopenia

Thomas G. DeLoughery, MD, MACP, FAWM

Professor of Medicine, Oregon Health & Science University, Portland, OR

Question 11

A 34-year-old man has been undergoing treatment for ITP over the past year. He has been treated with 2 courses of prednisone, which raised his platelet count to 75 x 103/μL, but with both courses the count decreased to 3 x 103/μL once the steroids were tapered. With low platelets, he has experienced increased bruising. Which of the following treatments is the best option for achieving long-term remission in this patient?

  •   Splenectomy
  •   Eltrombopag
  •   Intravenous immune globulin (IVIG) 1 g/kg once every 28 days
  •   Rituximab 375 mg/m2 weekly for 4 weeks
  •   Romiplostim

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