Advanced Stage and Relapsed/Refractory Hodgkin Lymphoma

Timothy S. Fenske, MD

Associate Professor of Medicine, Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI

Question 11

A 47-year-old man presents with high fevers and weight loss for 2 months. On examination, he is found to have cervical, supraclavicular, axillary, and inguinal lymphadenopathy. Laboratory work-up shows a hemoglobin level of 11.5 g/dL, white blood cell (WBC) count of 16,000 cells/μL, and a serum albumin level of 3.3 g/dL. Excisional biopsy of an inguinal lymph node is consistent with classical Hodgkin lymphoma (cHL).

Which of the following factors for this patient has not been shown to be an adverse prognostic marker?

  •   Age of 47 years
  •   Albumin level of 3.3 g/dL
  •   Hemoglobin of 11.5 g/dL
  •   WBC count of 16,000 cell/μL
  •   None of the above

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